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Mayo Clinic Graduate Research Employment Program - Limited Tenure in Rochester, Minnesota

City Rochester

State Minnesota

Telecommute No

Department Physiology & Biomedical Engineering

Why Mayo Clinic

The needs of patients drive research at Mayo Clinic. As doctors treat patients and see opportunities for advancing patient care, they work together with Mayo scientists and research teams to develop new and improved diagnostic tools, medications, devices, treatment protocols and more. Encouraging and including contributions from diverse individuals is critical to Mayo Clinic's future. By leveraging the strengths that each diverse individual and group brings to the table, Mayo Clinic gains the strategic advantages of accelerated innovation, better problem solving, enhanced productivity and job satisfaction, improved quality, and, most importantly, provides better ways to meet the needs of our patients.

Position description

The Graduate Research Employment Program (GREP) is a post-baccalaureate program for participants with an interest in biomedical research. The primary purpose of GREP is to provide a post-baccalaureate laboratory research experience that applies skills in science, technology, engineering or math to biomedical research including basic science or translational research. GREP participants gain research experience that may help them to decide on a career path related to biomedical research. In addition, the experience can increase the participants’ competitiveness and preparation for the next step in their career. These goals are achieved by providing:

• A mentored research experience in a world-class biomedical research laboratory

• Opportunities to participate in selected graduate classes and seminars

• Career development, mentoring and networking opportunities

• Presentation opportunities

Our integrative physiology laboratory seeks a highly motivated post-baccalaureate student to investigate the interrelationship between the pancreas and kidney in animals models of type 2 diabetes. In the current project, our group will test the hypothesis that in T2DM human β-cells increased expression of an electrogenic Na+/HCO3 cotransporter (NBCe1) encode by SLC4A4 gene leads to intracellular alkanization and metabolic adaptation towards glycolytic metabolism leading to loss of glucose-stimulated insulin secretion. The work will involve basic molecular biology (mutagenesis, cRNA), cellular electrophysiology, work with fluorescent genetically encoded sensors, in vivo ultrasound imaging, renal and pancreatic physiology measures and immunohistology.

The ideal student should have an aptitude for quantitative measurements and analysis. The student should be willing to work with animal models, accumulate & analyze large datasets (some programming) as well as working with a variety of biophysical techniques. Experience with programming in C++, MatLab or Python are a plus. Our goal is to provide rigorous training over 1-2 years for students interested in competitive PhD programs in Physiology and/or Biomedical Engineering.


• Bachelor’s degree with a strong background in science, technology, engineering, or math

• Interest in biomedical research

• Minimum GPA of 3.0

• Authorization to work and remain in the United States, without necessity for Mayo Clinic sponsorship now, or in the future (for example, be a U.S. citizen, national, or permanent resident, refugee or asylee)

• A current transcript submission required – unofficial transcripts will be accepted

• A 1-2 sentence statement of research interest

Students that do not meet these criteria do not qualify.

Applicants who are currently in Graduate or Medical School are not eligible.

Eligibility of applicants with advanced degrees above BA or BS depend on the specific degree

Exemption status Non-exempt

Compensation Detail This position has a predetermined rate of $15.50 per hour.

Benefits eligible Yes

Schedule Full Time

Hours / Pay period 80

Schedule details Monday - Friday 8 hour days; typically 8:00 a.m. - 5:00 p.m.

Weekend schedule As needed.

Site description

Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.

Category Clinical Labs and Research

Career profile Research

Job posting number 151333BR

Recruiter Chadwick Musolf

Equal opportunity

As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.