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Pfizer Senior Director, Vaccines R&D Data Sciences (AI/ML) in Pearl River, New York


You will provide AI/ML expertise and leadership to build strategy and lead a team that designs, implements, and maintains a comprehensive bioinformatics system to support modelling work and applies cutting-edge NGS capabilities and analysis pipelines to support Vaccines Research and Development. You will apply AI/ML models and other innovative digital solutions to enhance global viral surveillance, strain predictions based on genetic, antigenic, and relevant metadata, mRNA sequence optimization and antigen design, automated synthetic DNA/RNA biology workflows, and other scientific workstreams to support vaccine programs.


  • Provide AI/ML and computational biology expertise to support Vaccines Research and Development

  • Design, implement, and maintain a comprehensive bioinformatics system, including a sequence analysis pipeline, viral surveillance, strain prediction tools, and synthetic and automated DNA/RNA workflows

  • Interact with system users within Pfizer and coordinate efforts with the scientific and public health communities around AI/ML and bioinformatics

  • Assist with document preparation for regulatory, patent, and scientific presentations and submissions. Insure availability of required computational resources

  • Lead a team of Lab Scientists, Bioinformaticians, and Computational Scientists


  • PhD in Computer Science, Bioinformatics, Computational Biology, Software Engineering, Biotechnology Engineering or related discipline

  • Minimum of 10 years of experience building and maintaining advanced AI/ML models and experience in computational biology, comparative genomics, NGS workflow and analysis to support R&D

  • Experience managing a team and a diverse set of stakeholders, including scientific users and outside experts

  • Proficiency in mathematics, biostatistics, probability theory, data structures, and algorithms

  • Strong coding and programming skills in Python, Java, and R

  • Hands-on experience with popular AI/ML frameworks and libraries

  • Strong communication skills - written, report writing and verbal

  • Experience interacting and building relationships with colleagues (e.g., Vaccine Scientists, Bioinformaticians, business technology experts) and outside organizations (e.g., GISAID, CDC, WHO, and academic institutions)


  • Minimum 4 years directly related experience in a pharmaceutical environment

  • Strong knowledge of and experience in virology, particularly for respiratory pathogens (influenza and SARS-CoV-2), synthetic DNA/RNA biology


Strong cognitive and social skills, ability to learn and apply new computing technology, remember processes, maintain focus, complete tasks independently, make timely decisions in the context of a workflow, ability to communicate with colleagues coming from different disciplines, must be able to think rationally and apply logic during high stress situations.


Occasional travel for business meetings/conferences

Work Location Assignment:On Premise

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development