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We are looking for a medicinal chemist who can provide significant contributions to medicinal chemistry strategy and who will have a significant laboratory presence that is focused on enabling critical chemistry for Small Molecule project advancement. The ideal candidate will leverage their deep understanding of medicinal and synthetic chemistry and to help deliver high quality Small Molecule clinical candidates as part of Biogen’s research portfolio.

What You’ll Do

• Leverage your expertise in medicinal chemistry and organic synthesis to help deliver clinical candidates for high value Small Molecule programs

• Collaborate with team members to build the strategy to iteratively identify/design analogs that advance the project (pharmacology, ADME, safety) via the application of structure-based, ligand-based, property-based, and efficiency-based design.

• Work collaboratively with key functions such as DMPK, Biology, Chemical Biology and Proteomics, Bioassays and High Throughput Screens, and Physical Biochemistry to deliver optimal Small Molecule candidates.  

• Maintain a significant laboratory presence that is focused on identifying and enabling critical synthetic chemistry for advancing the project that can be used by chemistry CROs and the internal Biogen Parallel Medicinal Chemistry (library synthesis).

• Maintain an understanding of cutting edge synthetic chemistry and how it can be applied to their own project and other projects in the department.

• Leverage internal Synthesis Technologies resources such as High Throughput Experimentation, Parallel Medicinal Chemistry, and Purification to drive impactful synthesis strategies that advance their project.

• Oversee external chemistry CROs to maximize the efficiency of compound synthesis and characterization.

Who You Are

You are a medicinal chemist with experience in an industrial setting along with a proven track record of impactful contributions on small molecule drug discovery programs. You enjoy working in cross-functional teams to advance compounds towards clinical candidate selection.

Required Skills

• Ph.D. in organic or medicinal chemistry with minimum of 2 years biopharmaceutical medicinal chemistry experience or M.S. with a minimum of 5 years biopharmaceutical medicinal chemistry experience

• Demonstrated ability to influence project advancement. 

• Well-established track record of conducting innovative drug discovery research as evidenced through publications, patent applications, and presentations.

• Demonstrated ability to work effectively in a high-paced, collaborative environment with an ability to share and receive constructive feedback.

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.