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Senior Scientist (Ph.D.), ADC Biology

Why Patients Need You

At Pfizer we deliver breakthroughs that change patients' lives. The ADC Biology team plays a vital role in this mission through discovering and advancing novel ADCs while utilizing comprehensive biological evaluation of tumor associated antigens and linker payloads. To discover the next generation of therapeutics, we are seeking a highly collaborative scientific leader with expertise in cancer cell biology.

POSITION SUMMARY

The successful candidate will be responsible for designing and executing preclinical discovery research activities in collaboration with cross functional project teams for drug development candidates. This individual will directly contribute to Pfizer Oncology pipeline and will be expected to drive collaborative efforts with cancer biologists, immunologists, chemists, and protein engineers to innovate and develop first-in-class oncology therapies. The successful candidate should have a record of being a strong scientist, team player, strategic thinker, and an effective communicator.

KEY RESPONSIBILITIES

• Design, conduct, analyze, interpret and document experiments utilizing a diverse array of techniques aimed at identifying and characterizing novel tumor associated antigens and evaluating novel ADC payloads

• Execute molecular and cell-based methodologies including cytotoxicity assays, reporter assays, ELISA, western blotting, WES, in vitro PD assays, and flow cytometry

• Leverage cell surface target biology to guide therapeutic design and identify the appropriate preclinical models for therapeutic design validation

• Design and execute comprehensive experimental plans that inform and enable project progression. Define clear go/no go criteria for projects in alignment with overall research and corporate strategy

• Serve as a subject matter expert in cancer biology; stay abreast of relevant literature and act as an expert resource within research

• Work independently and demonstrate the ability to collaboratively contribute to projects outside their own expertise

• Present research results and methodologies at meetings with immediate supervisor and/or project leader, project team meetings and other research forums.

• Contribute to building a culture that embraces scientific excellence, urgency, continuous learning and improvement, increasing technical skill base and cancer biology expertise; take a proactive role in personal growth and scientific development

Basic Qualifications

• Ph.D. degree or equivalent experience in Cancer Biology, Cell biology, Biochemistry, Engineering or a related field

• Understanding of appropriate statistical design and analysis for pre-clinical experiments.

• Ability to identify and plan critical path experiments in alignment with team objectives.

Preferred Qualifications

• Post-doctoral training in Cancer Biology or a related field is strongly preferred.

• Uses critical thinking to solve complex problems, address challenges and overcome obstacles.

• Ability to adapt and adjust to a rapidly evolving environment.

• Highly effective interpersonal skills, ability to identify and absorb critical information and convey it to relevant stakeholders.

• Strong written and verbal communication skills with the ability to communicate effectively to a wide range of audiences.

The annual base salary for this position ranges from $88,300.00 to $147,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development