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Pfizer Senior Associate Scientist, Protein Solutions in Bothell, United States

Role Summary

We are seeking a senior associate scientist to assist with antibody purification and characterization. You will work with FPLC instrumentation as part of a core protein production group in the Research department. The focus of your job will purification and characterization of requested antibodies, along with protocol development and optimization while supporting other team sub-functions. Your work will play a critical role in supporting preclinical efforts in developing novel antibody-based therapeutics.

Role Responsibilities:

  • Routinely purify antibodies with AKTA Avant equipment.

  • Characterize products utilizing UPLC, HPLC, UV-vis, and Mass Spectrometry methods.

  • Create and update purification and characterization software protocols.

  • Process protein samples under sterile conditions in a biosafety cabinet.

  • Clean and perform preventative maintenance on purification instrumentation.

  • Complete general lab upkeep tasks and support inventory fulfilment.

  • Document work promptly using LIMS and ELN platforms.

Required Qualifications

  • BS and 3+ years' hands-on experience with FPLC purification techniques.

  • Basic understanding using Unicorn, Empower, or related software operation instructions.

  • Comprehension of two or more analytical chromatography techniques: size exclusion, hydrophobic interaction, reverse phase, UV-vis, endotoxin detection, dynamic light scattering, or SDS-PAGE.

  • Demonstrated ability to manage multiple tasks or projects with overlapping timelines.

  • Work in a team-based environment employing a solution-based approach.

Preferred Qualifications

  • 3+ years' experience working directly with AKTA instruments performing protein purification.

  • 1+ years' experience running HPLC or UPLC system or analyzing data results.

  • Aseptic technique processing samples in biosafety cabinet.

  • Write advanced Excel formulas and VBA or other coding languages.

  • Robotic handling using TECAN or Hamilton platforms.

Additional Information

  • Work Location Assignment: On Premise

  • Relocation Assistance Available

  • Last Day to Apply: September 19, 2024

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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