Job Information
Biogen Research Fellow, Biologics Drug Discovery in Cambridge, Massachusetts
About This Role
The Biologics Drug Discovery group at Biogen is seeking a creative and self-motivated research fellow to contribute to our mission to design, optimize, and develop medicines to transform patients’ lives. The Research Fellow role at Biogen is an 18-month position designed to provide a unique opportunity for scientists to gain exposure to drug discovery and development and train in an industry research setting. As a member of the Protein Chemistry group, you will work with a cross-functional team to design, optimize and produce antibody-oligonucleotide conjugates intended to improve delivery of therapeutic oligonucleotides (ASOs or siRNAs) to target tissues.
What You’ll Do
Optimize and implement protein purification schemes for engineered antibodies, including bispecific antibodies, using computer interfaced chromatography systems (e.g. AKTA or similar)
Characterize proteins using standard methods such as SDS-PAGE, analytical size-exclusion chromatography, and dynamic light scattering
Develop and optimize novel antibody-oligonucleotide conjugation methods
Generate, purify, and analyze antibody-drug conjugates for use in animal models.
As a member of a project team, contribute to strategy and experimental design, and regularly present your work at team meetings
Who You Are
The ideal candidate is a recent Ph.D. graduate with a passion for science and enthusiasm to work collaboratively with team members to make data-driven decisions. The candidate should be eager to acquire new skills and techniques.
Required Skills
Ph.D. in biochemistry or related field with 0-1 years of postdoctoral experience
Proficient in protein purification and characterization techniques
Protein conjugation experience
Ability to independently design, plan, execute, and interpret experiments
Strong written and verbal communication skills
Preferred Skills
- Experience working with oligonucleotides or conjugating oligos to proteins.
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.